Research Specialist
Johns Hopkins University

Job Info

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Research Specialist
The Department of Genetic Medicine is seeking a Research Specialist who will work in a molecular biology lab that integrates methodologies of epigenetics/ epigenomics and mouse models for translational discovery. The laboratory focuses on developing therapeutic opportunities for disorders of the histone machinery by manipulating the epigenome. Manipulation of the epigenome in mice with Mendelian disorders of the histone machinery.

The current focus is Kabuki syndrome a rare defect in an enzyme that has histone H3K4 methyltransferase function. Will make intellectual contribution to scientific research interests of the lab. In collaboration with PI, make research project decisions that may alter research objectives and direction. Contribute to writing peer-reviewed manuscripts and grants. Apply independent thought to make decisions with PI. Help lab run smoothly.

Specific Duties & Responsibilities:

• Conduct independent research projects relating to translational research to develop therapeutic approaches for Mendelian disorders of the histone machinery. Will also investigate fundamental truths on epigenetics by exploring the epigenetic consequences of these genetic defects.
• Perform sophisticated data analysis utilizing extensive knowledge base and varied methods experience.
• Act as consultant to refine or adapt methodologies to fit research objectives. Collaborates in development of new technologies, protocols and uses of equipment. Will use state of the art equipment including a Miseq, next generation sequencer, a pyrosequencer as well as working towards developing some novel mouse models through transgenic core.
• Contribute original thoughts, hypotheses, and analysis to write reports, abstracts and manuscripts.
• Function scientifically in lab similarly to post-doctoral fellow. Independently perform all research assays specific to the research laboratory interests.
• May provide work direction and support graduate student and postdocs.
• Make decisions regarding research projects that may require assessment, revision of objectives or altering scientific direction; considers resources and lab priorities when making decisions.
• Assist with monitoring inventory levels, orders materials and supplies, as needed.

Minimum Qualifications (Mandatory):

• Bachelor's Degree in Biology, Chemistry or related field.
• One year experience in a comparable laboratory performing relevant techniques.
• Master's Degree, with related graduate research, may substitute for experience to the extent permitted by the JHU equivalency formula.*

* JHU Equivalency Formula: 18 graduate degree credits may substitute for one year of experience. Additional related experience may substitute for the required education on the same basis. For jobs where equivalency is permitted, up to two years of non-related college course work may be applied towards the total minimum education/experience required for the respective job.

** Applicants who do not meet the posted requirements but are completing their final academic semester/quarter will be considered eligible for employment and may be asked to provide additional information confirming their academic completion date.

Preferred Qualifications:

• Ph.D. in Genetics or related field.

Special Knowledge, Skills & Abilities:

• Bacterial cloning, cell culture work, basic mouse work, PCR, Sanger sequencing, general molecular biology methods, flow sorting, chromatin immunoprecipitation.
• Pyrosequencing, next generation sequencing and analysis of large data sets.

Physical Requirements:

• Sitting in a normal seated position for extended periods of time.
• Reaching by extending hand(s) or arm(s) in any direction.
• Finger dexterity to manipulate objects with fingers rather than with whole hand or arm, for example, using a keyboard.
• Communication skills using the spoken word.
• Ability to see and hear within normal parameters.
• Ability to move about workspace.
• Lift, carry, move supplies, computers, glassware, etc.

Classified Title: Research Specialist
Role/Level/Range: ACRP/03/MA
Starting Salary Range: $16.28 - $22.38/hr (commensurate with experience)
Employee group: Casual / On Call
Schedule: M-F approximately 5 hours per week
Exempt Status: Non-Exempt
Location: School of Medicine Campus
Department name: SOM Genetics Institute of Gen Medicine
Personnel area: School of Medicine

The successful candidate(s) for this position will be subject to a pre-employment background check.

If you are interested in applying for employment with The Johns Hopkins University and require special assistance or accommodation during any part of the pre-employment process, please contact the HR Business Services Office at jhurecruitment@jhu.edu. For TTY users, call via Maryland Relay or dial 711.

Johns Hopkins has mandated COVID-19 and influenza vaccines, as applicable. Exceptions to the COVID and flu vaccine requirements may be provided to individuals for religious beliefs or medical reasons. Requests for an exception must be submitted to the JHU vaccination registry. For additional information, applicants for SOM positions should visit https://www.hopkinsmedicine.org/coronavirus/covid-19-vaccine/ and all other JHU applicants should visit https://covidinfo.jhu.edu/health-safety/covid-vaccination-information/.

The following additional provisions may apply, depending on campus. Your recruiter will advise accordingly.

The pre-employment physical for positions in clinical areas, laboratories, working with research subjects, or involving community contact requires documentation of immune status against Rubella (German measles), Rubeola (Measles), Mumps, Varicella (chickenpox), Hepatitis B and documentation of having received the Tdap (Tetanus, diphtheria, pertussis) vaccination. This may include documentation of having two (2) MMR vaccines; two (2) Varicella vaccines; or antibody status to these diseases from laboratory testing. Blood tests for immunities to these diseases are ordinarily included in the pre-employment physical exam except for those employees who provide results of blood tests or immunization documentation from their own health care providers. Any vaccinations required for these diseases will be given at no cost in our Occupational Health office.

Equal Opportunity Employer
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To apply, visit https://jobs.jhu.edu/job/Baltimore-Research-Specialist-MD-21205/823399700/





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