Head, Novel Gene Editing System Discovery and Engineering, Moderna Genomics
ModernaTX, Inc.

Cambridge, Massachusetts

Posted in Science and Research


This job has expired.

Job Info


The Role:

This is an exciting opportunity for a senior leader to build the Technology Discovery function within the newly created Moderna Genomics. The Head of Technology Discovery will work as a critical member of the Moderna Genomics Leadership Team to establish Moderna as a leader in in-vivo gene editing. She/he/they will build and develop a world-class team of scientists to advance and expand the company's genome-editing systems. The candidate will have a strong background in DNA replication and repair, genetic mobile element biology, CRISPR system, and a proven record of "think-outside-the-box" pioneering technology and developing methods. In addition to proposing and implementing research projects in a team environment, the candidate will make critical go/no-go decisions regarding these projects. This is an exciting and fast-paced position that will lead to new patents, journal publications, and scientific presentations to internal and external groups. Most importantly these new technology developments will used to create the next generation in vivo RNA based genomic medicines.

Here's What You'll Do:

  • Build the Technology Discovery function within Moderna Genomics, including hiring, leading and mentoring a team of researchers to develop novel gene editing systems and methodologies
  • Propose, compare, and decide amongst innovative approaches to develop CRISPR and non-CRISPR-based tools based on the needs of the company and in vivo gene editing field
  • Design, implement, and functionally characterize CRISPR and non-CRISRP-based tools for mammalian genome editing
  • Deploy developed technologies to researchers throughout the company
  • Collaborate with other scientists to perform and analyze mammalian genome editing experiments
  • Communicate results clearly and concisely, internally and externally
  • Keep accurate records of experiments and results

Here's What You'll Bring to the Table:
  • PhD in genetics, cell biology, biochemistry, molecular biology, or a closely related field
  • Extensive experience in academic, pharmaceutical or biotechnology company focused on gene editing tool development
  • Proven track record of design and development of novel CRISPR genome-editing systems and method development
  • Extensive experience in DNA structure and function; genetic mobile elements; molecular biology skills and knowledge
  • Strong background in protein engineering and directed evolution
  • Strong background in bioinformatics and genomic data analysis
  • Strong background in cell-based genome editing
  • Excellent interpersonal, verbal, and written communication skills
  • Strong desire to work on early-stage technology development, implementing creative thinking to build Moderna Genomics' genome-editing toolkit and patent portfolio
Additional positives:
  • Experience with Design of Experiment (DOE) methodologies
  • Experience performing protein mutagenesis and evolution
  • Experience with multiple modes of vector delivery (e.g., Lipid nanoparticle, viral vectors, nucleofection, etc.)
  • Familiarity with molecular visualization software (e.g., Pymol, CCP4, Chimera, etc.)
  • Experience with Next-generation sequencing (NGS) technologies

Here's What We'll Bring to the Table:
  • On-site subsidized cafeteria or catered lunches
  • Company-provided iPhone
  • Free parking, monthly subway pass or a subsidized commuter rail pass
  • Free annual corporate membership to Bluebikes
  • Highly competitive healthcare coverage including: medical offered through BCBS (HMO/PPO), dental, and vision offered through VSP
  • Flexible Spending Accounts for medical expenses and dependent care expenses
  • 16 weeks of 100% paid parental leave for all new parents
  • 16 weeks 100% paid family caregiver leave
  • 20 weeks 100% paid medical leave
  • Eligible for "Moderna Month" (one month paid sabbatical after five years of service and eligible for additional one month paid sabbatical every 3 years thereafter)
  • Adoption assistance and discounts to local childcare centers, as well as access to care.com
  • 401k (traditional and Roth offered) with 50% match on first 6% deferred. Match is vested immediately
  • A suite of Moderna paid insurance coverage, including: life insurance, short-term and long-term disability
  • Voluntary legal assistance plan
  • 15 days' vacation and 7 sick days per year, in addition to a discretionary winter shut down and 11 company paid holidays (includes 2 floating holidays)

Candidates should be aware that Moderna currently maintains a policy requiring all US-based employees to be fully vaccinated against COVID-19 and receive a booster shot once eligible. Newly hired employees must be vaccinated and boosted prior to their employment start date. Moderna is an equal opportunity employer and will provide a reasonable accommodation to those unable to be vaccinated or receive a booster where it is not an undue hardship to the company to do so as provided under federal, state, and local law.

About Moderna

In 10 years since its inception,Modernahas transformed from a science research-stage company advancing programs in the field of messenger RNA (mRNA), to an enterprise with a diverse clinical portfolio of vaccines and therapeutics across six modalities, a broad intellectual property portfolio in areas including mRNA and lipid nanoparticle formulation, and an integrated manufacturing plant that allows for both clinical and commercial production at scale and at unprecedented speed.Modernamaintains alliances with a broad range of domestic and overseas government and commercial collaborators, which has allowed for the pursuit of both groundbreaking science and rapid scaling of manufacturing. Most recently, Moderna's capabilities have come together to allow the authorized use of one of the earliest and most effective vaccines against the COVID-19 pandemic.

Moderna's mRNA platform builds on continuous advances in basic and applied mRNA science, delivery technology and manufacturing, and has allowed the development of therapeutics and vaccines for infectious diseases, immuno-oncology, rare diseases, cardiovascular diseases and auto-immune diseases.Modernahas been named a top biopharmaceutical employer bySciencefor the past seven years. To learn more, visit www.modernatx.com.

Moderna is a smoke-free, alcohol-free and drug-free work environment.

Moderna is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation or any characteristic protected under applicable law. Moderna will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.

#LI-KF1
-


This job has expired.

More Science and Research jobs


Circana
Chicago, Illinois
$84,000.00 - $135,000.00 per year
Posted about 5 hours ago

Circana
Waterloo, New York
$15.00 per hour
Posted about 5 hours ago

Circana
Chicago, Illinois
$47,000.00 - $75,000.00 per year
Posted about 5 hours ago

Get Hired Faster

Subscribe to job alerts and upload your resume!

*By registering with our site, you agree to our
Terms and Privacy Policy.